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What is PDRN?

PDRN (Polydeoxyribonucleotide) is one of the hottest ingredients in Korean skincare right now, especially for skin regeneration and anti-aging.
Originally used in dermatology and medical treatments, PDRN helps stimulate skin healing, collagen production, and improves elasticity.

In K-beauty, PDRN is now included in serums, ampoules, and creams to repair damaged skin, reduce fine lines, and restore a youthful glow.


Benefits of PDRN in Skincare

  • Stimulates cell regeneration

  • Boosts collagen synthesis

  • Improves skin elasticity and firmness

  • Reduces fine lines and wrinkles

  • Accelerates healing after skin damage (acne, procedures, irritation)

  • Safe for sensitive skin types


Korean Skincare Brands That Use PDRN

Let’s explore the top Korean products that contain PDRN and are available right now:


1️⃣ VT Cosmetics

Star product:

  • VT Pro Cica PDRN Ampoule

Why it's great:

  • Combines PDRN with Cica (Centella Asiatica) for powerful skin barrier repair.

  • Soothes redness, accelerates healing, and improves skin texture.

  • Lightweight, non-greasy formula perfect for daily use.

K-Kare Recommendation:
Shop VT Pro Cica PDRN Ampoule


2️⃣ Medicube

Star product:

  • Medicube Super Cica PDRN Serum

Why it's great:

  • High concentration of PDRN to support skin elasticity.

  • Targets sagging skin and improves skin density.

  • Excellent for mature skin or after treatments like microneedling.

K-Kare Recommendation:
Shop Medicube Super Cica PDRN Serum


3️⃣ Abib

Star product:

  • Abib Jericho Rose PDRN Ampoule

Why it's great:

  • Combines PDRN with hydrating rose extract.

  • Repairs damaged skin while deeply hydrating.

  • Soothes irritated skin and improves skin tone.

K-Kare Recommendation:
Shop Abib Jericho Rose PDRN Ampoule


4️⃣ Numbuzin

Star product:

  • Numbuzin No.6 Deep Sleep Mask Serum

Why it's great:

  • Contains PDRN alongside peptides and adenosine.

  • Works overnight to repair skin while you sleep.

  • Helps restore elasticity and firmness.

K-Kare Recommendation:
Shop Numbuzin No.6 Deep Sleep Mask Serum


Is PDRN Safe for Daily Use?

Yes. PDRN is well-tolerated by most skin types, including sensitive skin.
It’s often recommended for:

  • Post-acne skin

  • Skin recovering from laser or microneedling

  • Mature skin concerned with sagging and fine lines

  • Damaged or irritated skin barrier


👉 Explore our full range of Korean PDRN skincare products at K-Kare Spain.

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